Tru Niagen® 300mg

Age Better® and boost NAD+ levels with the minimum daily recommended serving of Niagen®, our patented nicotinamide riboside (NR).

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    Age better with Tru Niagen.

Clinically proven to increase NAD+ by 51% in 2 weeks

Patented high-absorption Niagen delivers proven, reliable results unlike NAD+ itself, NMN, and experimental liposomal supplements.

The only FDA reviewed and GRAS certified NR in the world.

Clean ingredients and rigorous third-party testing you can trust.

Backed by 25+ years of research & innovation

From the NAD+ authority trusted by physicians, athletes, researchers, and a Nobel Prize-winning biochemist.

  • 45+

    Human Clinical Studies on Niagen® NR

  • 60+

    Proprietary NR Patents

  • 500+

    Published Scientific Studies

  • 300+

    Global Research Collaborations

    THE SCIENCE BEHIND NAD+

    Every cell in your body is fueled by NAD+

    Your 37.2 trillion cells are powered by NAD+, a vital coenzyme that fuels cellular energy and repair throughout your entire body. NAD+ levels naturally decline with age, lifestyle factors, and stressors. Replenishing NAD+ levels is essential for maintaining your cellular health, energy, and vitality.

    MEET OUR STAR SUPERNUTRIENT

    The #1 NAD+ booster³

    Discover Tru Niagen, a revolutionary supplement backed by decades of research and clinically proven to increase NAD+ up to 150% to keep your cells performing at their best.



    Powered by Niagen®, our patented form of nicotinamide riboside, Tru Niagen is one of the most well-researched, efficient, and superior NAD+ precursors available, ensuring you get the best for your health.

    Whole-body benefitsFrom your daily

    • Healthy Aging'

      Boost NAD+ levels for energized,
      resilient cells,ready for repair at any
      time.

    • Brain'

      Power your hardworking brain cells with
      increased cellular energy.

    • Heart't

      Support your heart cells with the
      essential care they need for cellular
      resilience.

    • Muscle'

      Energize muscle cells to help fuel
      muscle recovery and repair.

    • Cellular Health'

      Support your 37.2 trillion cells with
      increased NAD+ for energy and repair.

    • Lifestyle Stress Management*+

      Help counter the impact of
      physiological stress on your cells that
      further deplete NAD+.

      "Niagen, Niagen Bioscience's patented nicotinamide riboside product, is one of the most well studied,carefully controlled dietary supplements, and indeed, a gold standard in the industry."

      Roger Kornberg,Ph.D.

      Nobel Prize Winner in Chemistry | Mrs.George A.Winzer Professor of Medicine,Stanford|
      Niagen Bioscience Scientific Advisory Board Chairman

      "Disturbances in NAD coenzymes can leave tissues unable to repair themselves, generate energy, and perform their normal homeostatic functions. In many conditions of metabolic stress, the genes that convert NR to NAD are up-regulated,which provides unique value over all other NAD precursors."

      Charles Brenner, Ph.D.

      Charles Brenner,PhD,Professor of Metabolic Regulation,Faculties of Medicine,Pharmacy and Helsinki Instituteof Life Science,University of Helsinki,Finland,and Chief Scientific Advisor at Niagen Bioscience

      "With the clear preclinical benefits of NR observed in the brains of mice, I look forward to future clinical trial findings from testing in human subjects. In the meantime, the known ability of NR to enhance mitochondrial function and cellular energy makes it a top choice for my personal daily regimen."

      Dr.Rudolph Tanzi

      Kennedy Professor of Neurology,Harvard University |Director,Genetics and Aging Research Unit, Massachusetts General Hospital| Niagen Bioscience Scientific Advisory Board Member

      "Tru Niagen stands out as the leading, gold-standard NAD+ supplement.. crucial for maintaining cellular resilience, energy metabolism, and overall cellular repair. Further, it features patented nicotinamide riboside (NR),which is the most efficient NAD+ precursor available."

      Dr. Jim LaValle

      Clinical Pharmacist |CEO of Metabolic Code Enterprises|Former Niagen Bioscience
      Consultant

      Frequently Asked Questions

      What is NAD+ and how does it work?

      NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.

      What are the potential benefits of taking NAD+ supplements?

      NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.

      What is the difference between Tru Niagen and other NAD brands on the market?

      What is the difference between Tru Niagen and other NAD brands on the market?
      Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 45+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels. 
      This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically shown to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.

      How quickly can I expect to see results from taking Tru Niagen?

      Cellular NAD+ support begins immediately upon supplementation. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.  
      Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine. 

      Is Tru Niagen safe, and are there any side effects

      Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.  
      Niagen is supported by 45+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 75% of published peer-reviewed clinical studies on NR use Niagen® NR. Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded. 
      In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications

      What are the benefits of subscribing to Tru Niagen

      Subscribers enjoy exclusive savings of 20% off every order, free shipping, and automatic delivery of Tru Niagen every month on your schedule. You can pause, skip, or adjust your subscription any time, risk-free. It’s the easiest way to ensure consistent NAD+ support for your daily health, while saving on every bottle.

      How does the 300mg dose compare to other available servings like 1000mg Pro?

      Tru Niagen 300mg features the key active ingredient, Niagen® and is our foundational serving size and clinically shown to increase NAD+ levels.  Other serving size option such as 150mg or 1000mg are other options for people who may want smaller capsule size in the 150mg, or choose a higher serving found in the Tru Niagen Pro 1000mg based on your lifestyle or age.  
      Everyone’s health needs vary and it’s recommended to work closely with your healthcare provider to determine the best serving size for your health goals. The ideal serving for you depends on your lifestyle, your age, and other factors. Try taking our Product Quiz to see what serving might be right for you. 
      The Conze et al., 2019 clinical study supplemented participants with 100mg, 300mg, or 1000mg of Niagen daily. NAD+ increased over 50% in 2 weeks and was maintained throughout the 8-week study with 300mg, and up to 150% with 1000mg.